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The pH at which an amino acid exists predominantly as a neutral dipolar zwitterion and does not migrate toward either electrode in an electric field:
$$\text{pI} = \frac{\text{p}K_{a1} + \text{p}K_{a2}}{2}$$
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The pH at which an amino acid exists predominantly as a neutral dipolar zwitterion and does not migrate toward either electrode in an electric field:
$$\text{pI} = \frac{\text{p}K_{a1} + \text{p}K_{a2}}{2}$$
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