In the equation given below, which 2 signs need to be interchanded so that it is balanced?
$$\frac{1}{4} \div \frac{1}{16} - 5 + 45 \times 25 = 40$$

A

$$\div$$ and $$\times$$

B

$$+$$ and $$−$$

C

$$\times$$ and $$−$$

D

$$+$$ and $$\times$$