Select the correct combination of mathematical signs to replace the * signs and to balance the given equation.
46*16*4*21*72*4*57

A

=, $$\times$$,+,+,$$\div$$,−

B

$$\div$$,=,−,$$\times$$,−,+

C

−,+,$$\times$$,=,−,+

D

+,=,−,$$\times$$,−,+