Select the correct combination of mathematical signs that can sequentially replace the * signs and balance the given equation.
216 * 6 * 8 * 64 * 48 = 500

A

$$\div, -, \times, +$$

B

$$\div, +, \times, -$$

C

$$\times, +, \div, -$$

D

$$\times, +, -, \div$$