In the following passage, some words have been deleted. Read the passage carefully and select the most appropriate option to fill in each blank.

Calcium supplements, commonly (1) _______women are helpful (2) ________ warding off osteoporosis. More than just (3) ________ grams a day, (4) ________, can lead to stomach upset and even kidney stones. Niacin proven in reducing cholesterol levels can be dangerous (5) ________doses to those who suffer from heart problems.