Instructions

The five sentences labelled (1, 2, 3, 4, 5) given in this question, when
properly sequenced , form a coherent paragraph . Each sentence is labelled
with a number. Decide on the proper order for the sentences and key in
this sequence of five numbers as your answer.

Question 166

1. Scientists have for the first time managed to edit genes in a human embryo to repair a genetic mutation, fueling hopes that such procedures may one day be available outside laboratory conditions.
2 . The cardiac disease causes sudden death in otherwise healthy young athletes and affects about one in 500 people overall.
3. Correcting the mutation in the gene would not only ensure that the child is healthy but also prevent transmission of the mutation to future generations.
4. It is caused by a mutation in a particular gene, and a child will suffer from the condition even if they inherit only one copy of the mutated gene.
5. In results announced in Nature this week, scientists fixed a mutation that thickens the heart muscle, a condition called hypertrophic cardiomyopathy.

We will first try to find the introductory sentence and then form pairs.

Sentence 1 forms a good introductory sentence, introducing the fact that scientists have been successful in editing a gene in a human embryo.

Sentence 5 follows up on the above sentence, mentioning that the finding has been published in 'Nature'.

Sentence 5 ends with the mention of a disease- hypertrophic cardiomyopathy and the sentence 2 mentions more about this disease.

Sentence 4 mentions the cause of the disease as a genetic mutation.

Sentence 3 tells what impact fixing this mutation would have.

Therefore, 15243 is the correct sequence describing the chain of events. 

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