The correct match between items of List-I and List-II is:

We match each vitamin (List-I) with the disorder produced when that vitamin is deficient (List-II).

Case A: Vitamin B1 (thiamine)
Deficiency leads to the nervous-muscular disorder called beriberi. Hence A → R.

Case B: Vitamin C (ascorbic acid)
This vitamin is needed for the hydroxylation of proline and lysine during collagen synthesis. Its deficiency weakens connective tissue and causes bleeding gums, giving the disease scurvy. Hence B → S.

Case C: Vitamin D (calciferol)
It regulates $$\mathrm{Ca^{2+}}$$ and $$\mathrm{PO_4^{3-}}$$ absorption and bone mineralisation. Lack of Vitamin D produces soft, demineralised bones—rickets in children (and osteomalacia in adults). Hence C → P.

Case D: Vitamin K (phylloquinone)
Vitamin K is required for the post-translational γ-carboxylation of several clotting factors. Deficiency prolongs clotting time, leading to excessive bleeding or haemorrhage. Hence D → Q.

The correct complete matching is therefore:
A → R, B → S, C → P, D → Q.

Among the given options, this correspondence is exactly the one stated in Option B.

Final Answer: Option B which is: (A)-(R), (B)-(S), (C)-(P), (D)-(Q)