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Question 43

To inhibit the growth of tumours, identify the compounds used from the following:
(A) EDTA
(B) Coordination Compounds of Pt
(C) D-Penicillamine
(D) Cis - Platin
Choose the correct answer from the option given below:

We need to identify compounds used to inhibit the growth of tumours.

Analysis of each compound:

(A) EDTA: Used as a chelating agent for removing heavy metals from the body (chelation therapy), not specifically for tumour inhibition.

(B) Coordination Compounds of Pt: Platinum-based coordination compounds are widely used as anticancer drugs. Examples include cisplatin, carboplatin, and oxaliplatin. Used for tumour inhibition. ✓

(C) D-Penicillamine: Used for treatment of Wilson's disease and rheumatoid arthritis (as a chelating agent), not for tumours.

(D) Cis-Platin: Cisplatin (cis-[PtCl$$_2$$(NH$$_3$$)$$_2$$]) is one of the most effective anticancer drugs. It inhibits DNA replication in cancer cells. Used for tumour inhibition. ✓

Note: Cis-platin (D) is itself a coordination compound of Pt (B), so both B and D are correct.

The correct answer is Option 1: B and D Only.

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