The number of integers greater than 2000 that can be formed with the digits 0, 1, 2, 3, 4, 5, using each digit at most once, is

Case 1: 4-digit numbers

Given digits - 0, 1, 2, 3, 4, 5

_, _, _, _

As the numbers should be greater than 2000, first digit can be 2, 3, 4 and 5.

For remaining digits, we need to arrange 3 digits from the remaining 5 digits, i.e. 5*4*3 = 60 ways

Total number of possible 4-digit numbers = 4*60 = 240

Case 2: 5-digit numbers

_, _, _, _, _

First digit cannot be zero.

Therefore, total number of cases = 5*5*4*3*2 = 600

Case 3: 6-digit numbers

_, _, _, _, _, _

First digit cannot be zero.

Therefore, total number of cases = 5*5*4*3*2*1 = 600

Total number of integers possible = 600 + 600 + 240 = 1440

The answer is option A.