Study the following information carefully and answer the question which follows:
Number of deaths due to ABN poisoning has risen in village A from 23 two years ago, to 67 this year. Since the number of patients is the same, it can be concluded that the new medication is the responsible factor for the deaths.
Which of the following statements weakens the given statements that the new medication Is responsible for increased number of fatalities?

While azethorin-1 was being used to treat ABN poisoning since 5 years, azethorin-6 was introduced last year after it obtained necessary clinical approvals.

PB released from a new fertilizer being used by the farmers of the village this years, when combined with ABN renders all types of medicines ineffective to treat the disease.

Due to low awareness regarding the disease, very low patients have been reporting this disease for many years which proves that the actual numbers could be much higher.

The new medicines introduced in village A for TQW and RST poisoning has been successful in significantly bringing down the fatality rate.

A cement factory set up 5 years ago in the village was responsible for leaching ABN in the soil as well as drinking water way above the danger limit.